Virtual Library

Start Your Search

N. Schmidt-Hegemann



Author of

  • +

    Poster Display session (Friday) (ID 65)

    • Event: ELCC 2018
    • Type: Poster Display session
    • Track:
    • Presentations: 2
    • Moderators:
    • Coordinates: 4/13/2018, 12:30 - 13:00, Hall 1
    • +

      84P - Patterns of care for patients with small cell lung cancer: A survey of German radiation oncology institutions on recommendations for prophylactic cranial irradiation (ID 471)

      12:30 - 13:00  |  Author(s): N. Schmidt-Hegemann

      • Abstract
      • Slides

      Background:
      Prophylactic cranial irradiation in SCLC was first proposed in 1973 and is recommended for patients demonstrating good response to initial therapy. The general pattern of care amongst radiation oncologists in Germany has not been previously evaluated. We conceptualized and conducted this survey to assess patterns of care.

      Methods:
      We surveyed radiation oncology institutions in Germany via an online questionnaire sent by e-mail to member institutions of the German Society for Radiation Oncology (DEGRO e.V.). The questions were based on respondent and treatment characteristics with emphasis on prophylactic cranial irradiation in limited- and extensive-stage SCLC.

      Results:
      We received a total of 95 responses (29% response rate). Of which 64 were completed and returned and hence eligible for evaluation. Sixty-one percent of respondents were between the ages of 50–59, 88% with over 15 years of experience in the management of lung malignancies. Sixty-seven percent of the institutions stage their patients initially with 18F-FDG-PET/CT. Of the 64 responses, 97% recommended delivery of PCI in therapy responders with LS-SCLC compared to 67% with ES-SCLC. Interestingly, a quarter of respondents offered hippocampal-avoidance PCI with only 38% following their patients with serial brain imaging following PCI. Neuropsychological testing was generally not routinely performed.

      Conclusions:
      German radiation oncology institutions showed interesting variations in certain aspects yet in general congruence in SCLC management and PCI delivery in accordance with the updated national and international guidelines. Future randomized clinical trials will further reduce discrepancies regarding delivery of PCI especially in ES-SCLC.

      Clinical trial identification:


      Legal entity responsible for the study:
      University Hospital, LMU Munich

      Funding:
      Has not received any funding

      Disclosure:
      All authors have declared no conflicts of interest.

      Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.

    • +

      86P - Prophylactic cranial irradiation in SCLC: A survey of German radiation oncology institutions on recommendations for brain imaging (ID 573)

      12:30 - 13:00  |  Author(s): N. Schmidt-Hegemann

      • Abstract
      • Slides

      Background:
      Prophylactic cranial irradiation in SCLC is recommended in therapy responders to primary treatment. The landmark PCI trials largely took place in the pre-MRI era. Recently, the role of brain imaging in PCI has come under increased scrutiny. We conducted this survey to gauge the patterns of brain imaging in PCI amongst radiation oncologists in Germany.

      Methods:
      We surveyed radiation oncology institutions in Germany via an online questionnaire sent by e-mail to member institutions in the online directory of the German Society for Radiation Oncology (DEGRO e.V.). The questions covered aspects of brain imaging in limited- and extensive-stage SCLC.

      Results:
      We received a total of 39 responses. Of which 34 were completed and eligible for further evaluation. 97% and 92% of respondents recommended brain imaging prior to initial treatment in LS- and ES-SCLC, respectively with contrast-enhanced MRI being the preferred modality in 86% of cases. Ninety-one percent of respondents recommended brain imaging not older than 4 weeks prior to PCI delivery with 71% recommending commencing PCI <4 weeks after primary treatment. Of all responses, 38% followed their patients regularly with serial brain imaging following PCI with the absolute majority preferring image acquisition only in symptomatic patients. On detection of brain metastases (BMs), 59% recommended stereotactic radiosurgery (SRS) or repeat whole brain radiotherapy depending on the number of BMs.

      Conclusions:
      Patterns of brain imaging in Germany are in general consistent with the guidelines with contrast-enhanced MRI being the preferred modality for brain staging prior to primary treatment and especially after multimodality treatment and before PCI delivery.

      Clinical trial identification:


      Legal entity responsible for the study:
      University Hospital, LMU Munich

      Funding:
      Has not received any funding

      Disclosure:
      All authors have declared no conflicts of interest.

      Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.