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K. Madan

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    Poster Display session (Friday) (ID 65)

    • Event: ELCC 2018
    • Type: Poster Display session
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 4/13/2018, 12:30 - 13:00, Hall 1
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      41P - Gender based variations in presentation and management of lung cancer at a south Asian tertiary referral centre (ID 447)

      12:30 - 13:00  |  Author(s): K. Madan

      • Abstract

      The clinical presentation and management strategies of lung cancer for lesser income women in South Asia has rarely been evaluated. We sought to compare the baseline characteristics, duration of symptoms, histology, staging, and rates of treatment between women and men at our public tertiary referral center in northern India.

      A retrospective review of patients diagnosed with lung cancer between January 1, 2008 and December 31, 2016 was completed. Baseline variables, previous treatment for tuberculosis, length of symptoms, tumor characteristics, and forms of treatment were collected and compared between women and men.

      1370 total patients were selected including 230 females (16.8%). Compared to men, women were younger (mean {SD} age, 54.6 {10.9} vs. 58.4 {10.8}; p < 0.001), less likely current or previous smokers (34.1% vs. 86.1%; p < 0.001), had a lower rate of secondary education (46.3% vs. 69.4%, p < 0.001), and increased rate of previous tuberculosis treatment (37.3% vs. 29.6%, p = 0.03). No differences in duration (p = 0.47) of symptoms at time of diagnosis, rates (p = 0.92) of non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), or rates (p = 0.20) of ultimately receiving some form of cancer treatment between women and men were observed. Women had higher rates of stage IV disease (75.0% vs. 62.2%, p < 0.001) for NSCLC but shared no difference (p = 0.48) in rates of extensive stage for SCLC compared to men.

      Women with lung cancer in our region are younger, more likely non-smokers, less well educated, more likely to have received recent anti-tuberculosis therapy before being correctly diagnosed, and more likely to present with metastatic disease. Clinicians should maintain a high index of suspicion even in younger women presenting with new-onset respiratory symptoms which may mimic tuberculosis.

      Clinical trial identification:

      Legal entity responsible for the study:

      Has not received any funding

      All authors have declared no conflicts of interest.