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Anna Maria Romaszko-Wojtowicz



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    P1.06 - Epidemiology/Primary Prevention/Tobacco Control and Cessation (ID 692)

    • Event: WCLC 2017
    • Type: Poster Session with Presenters Present
    • Track: Epidemiology/Primary Prevention/Tobacco Control and Cessation
    • Presentations: 1
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      P1.06-004 - Occurrence of Lung Cancer among Young Patients Below the Age of 50 – A Retrospective Analysis (ID 8040)

      09:30 - 16:00  |  Presenting Author(s): Anna Maria Romaszko-Wojtowicz

      • Abstract
      • Slides

      Background:
      Lung cancer is the leading cause of death worldwide in both women and men. According to the guidelines of the Polish National Cancer Registry in 2013, it is estimated that lung cancer had first place in oncological morbidity of men and third of women. The aim of the study was to evaluate the occurrence of lung cancer retrospective analysis in a group of patients before the age of 50. Patients had confirmed lung cancer diagnosis and were hospitalized in Center for Pulmonary Disease in Olsztyn between October 2014 and March 2017.

      Method:
      A retrospective analysis of 1,622 medical history patients who were hospitalized in the center at that time with histopathologically confirmed diagnosis of lung cancer. We selected only the patients who were diagnosed before the age of 50. The inclusion criteria were met by 23 patients: 7 women and 16 men. We analyzed: age, gender, symptoms, risk factors, including family history and additional diseases, type, stage, and survival.

      Result:
      We identified 23 cases of lung cancer before the age of 50, which was 1.41% of all patients diagnosed with lung cancer. There were 12 cases of small cell carcinoma, 6 cases of adenocarcinoma, 4 cases of squamous cell carcinoma and 1 case of NOS (Not Otherwise Specified). The majority (78%) of the respondents had a positive history of smoking - 2 of them quit smoking, the average pack-years was 31 (SD 13.72). A positive family history was reported in 11 individuals, while exposure to harmful environmental factors at work in 12 subjects. Prior to the diagnosis of cancer, 15 out of 24 patients had reported respiratory symptoms such as dyspnoea, cough, hemoptysis, or weight loss. Out of these 23 patients: 12 have died - their average lifetime from the moment of diagnosis till death was 6.45 months (SD 2.98)

      Conclusion:
      1. The incidence of lung cancer below the age of 50 years is 1.41% of all patients hospitalized with the diagnosed of lung cancer at that time. 2. Most common, in patients diagnosed with lung cancer below the age of 50, is small cell carcinoma 52.17%. 3. Most of the patients had a positive history of smoking (78%) and often additional factors such as family history (47%) or workplace exposure (52%); the total percentage was 91%. 4. Most (78%) of lung cancers were diagnosed in an advanced non-operative stage. 5. The average lifetime from the moment of diagnosis till death was 6.45 months.

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