Author of

• 20039

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  Poster Display Session (ID 63)

  • Event: ELCC 2017
  • Type: Poster Display Session
  • Track:
  • Presentations: 1
  • Moderators:
  • Coordinates: 5/07/2017, 12:30 - 13:00, Hall 1

  • 19842

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    69P - CT-Guided radiofrequency ablation of early stage NSCLC (ID 168)

    12:30 - 13:00  |  Author(s): X. Zhang
    • Abstract

    Background:
    To prospectively evaluate the safety and efficacy of radiofrequency (RF) ablation of early stage NSCLC with diameter of less than 30 mm.
    
    Methods:
    Forty patients (24 men and 16 women; age range, 35–78 years; mean age, 58 years) with early stage NSCLC (40 lesions) which were conformed by biopsy were enrolled in during 2014-2016. RF ablation was performed in tumors by CT guidance, each with a diameter of less than 30 mm (mean deviation, 14 mm). Written informed consent was obtained in this prospective study that was approved by the local ethics committee. Follow-up CT scans were obtained within 48 hours after treatment and at 2 and 6months thereafter to evaluate treatment outcome and complications. Lung spirometry measurements were obtained before and 2 months after RF ablation.
    
    Results:
    Forty successful RF ablation treatments were performed. The complications occured in the periprocedural period were 9 cases of minor pneumothorax and 4 cases of sputum cruentum. There were 35 lesions of reduced size, 13 lesions of stabilized lesion size, and 2 lesions of increased size on the follow-up Contrast-enhanced CT images at 6-month. There was no modification of respiratory function was found between the spirometry measurements before the treatment and 2 months after (P < 0.05).
    
    Conclusions:
    RF ablation is a safe and effective method to treat early stage NSCLC with diameter of less than 30 mm. Larger studies are necessary to fully evaluate its potential combination with other treatment techniques.
    
    Clinical trial identification:
    
    
    Legal entity responsible for the study:
    Xiaobo Zhang
    
    Funding:
    The Radiology Department of Chinese PLA General Hospital
    
    Disclosure:
    The author has declared no conflicts of interest.