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J. Ye



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    P1.04 - Poster Session with Presenters Present (ID 456)

    • Event: WCLC 2016
    • Type: Poster Presenters Present
    • Track: Pulmonology
    • Presentations: 1
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      P1.04-016 - EBUS plus Fluoroscopy-Guided Biopsy Compared to Fluoroscopy-Guided TBB for Obtaining Samples of Peripheral Pulmonary Lesions (ID 3739)

      14:30 - 15:45  |  Author(s): J. Ye

      • Abstract

      Background:
      Early detection of peripheral pulmonary nodules and histopathologic diagnosis of biopsy samples of the nodules are key to improving survival rates of lung cancer. Steady improvement in bronchoscopic procedures during the past few decades enable detection and biopsy of much smaller nodules. We report a meta-analysis of recent reports comparing the diagnostic yields of endobronchial ultrasonography plus fluoroscopically-guided transbronchial biopsy with that of fluoroscopically-guided transbronchial biopsy without the use of endobronchial ultrasonography.

      Methods:
      We searched Medline, the Cochrane Library, PubMed, and Google Scholar and found five articles that met our inclusion criteria. One of those articles did not strictly meet our criteria, in that it was deficient in quantitation, but we included it because it contained other relevant information.

      Results:
      Meta-analysis from the 4 studies revealed a higher positive diagnostic yield in the group with endobronchial ultrasonographic guidance in addition to fluoroscopy than the group diagnosed with only conventional fluoroscopic guidance to the lesion, for large and small lesions.

      Conclusion:
      Obtaining transbronchial biopsy samples for histopathological diagnosis is enhanced by addition of endobronchial ultrasonography to conventional fluoroscopic guidance; this is especially important for patients with small peripheral lung lesions who benefit greatly from early diagnosis.