Virtual Library

Start Your Search

E. Ionela Mihaela



Author of

  • +

    P1.04 - Poster Session with Presenters Present (ID 456)

    • Event: WCLC 2016
    • Type: Poster Presenters Present
    • Track: Pulmonology
    • Presentations: 1
    • +

      P1.04-010 - Neutrophil to Lymphocyte, Platelet to Lymphocyte Ratios and Systemic Inflammation in Lung Cancer Stages (ID 6169)

      14:30 - 15:45  |  Author(s): E. Ionela Mihaela

      • Abstract
      • Slides

      Background:
      Lung cancer is associated with systemic inflammation which seems to influence the prognostic of the disease. Different affordable methods may be used to evaluate the systemic inflammation: erythrocyte sedimentation rate (ESR), Neutrophil to lymphocyte ratio (Ne/Ly), Platelet to lymphocyte ratio (Pl/Ly). The aim of the study is to assess the relation between TNM lung cancer stages and the systemic inflammation estimated by Ne/Ly, Pl/Ly and ESR.

      Methods:
      Patients with lung cancer were classified according to 7[th] TNM lung cancer staging in two groups: Group A (I, II and IIIA) and Group B (IIIB, IV). A complete blood count (CBC) and ESR were determined. Ne/Ly and Pl/Ly ratios were calculated for all patients. The results were compared between the two groups.

      Results:
      73 consecutive patients (22 in Group A and 51 in group B) were analyzed. In Group A (16 males), the mean age was 63,73 ± 7,69 years, the median Ne/Ly: 2,86 (0,88-8,36), median Pl/Ly: 128,81 (21,62-416,67) and median ESR: 10 mm/h (10-120). In Group B (48 males), the mean age was 65,06 ± 10,09 years, the median Ne/Ly: 4,46 (0,70-25,6), median Pl/Ly: 204,48 (3,38-651,25) and median ESR: 40 mm/h (3-120). The values of Ne/Ly, Pl/Ly were significantly higher (p: 0,009 respectively p: 0,007) in Group B versus Group A, but no statistically significant difference was observed for ESR values.

      Conclusion:
      We found a relation between TNM lung cancer stages and the systemic inflammation assessed by neutrophil to lymphocyte (Ne/Ly) and platelet to lymphocyte (Pl/Ly) ratios. The values of Ne/Ly, Pl/Ly ratios were significantly higher in nonresectable stages (IIIB, IV).Erythrocyte sedimentation rate (ESR) seems not to be an appropriate method to evaluate this relation.

      Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.