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J.M. Ko
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P1.03 - Poster Session with Presenters Present (ID 455)
- Event: WCLC 2016
- Type: Poster Presenters Present
- Track: Radiology/Staging/Screening
- Presentations: 1
- Moderators:
- Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)
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P1.03-016 - Diagnostic Accuracy of Visual Assessment on Growth of Non-Measurable Target Pulmonary Nodules According to RECIST Criteria (ID 4683)
14:30 - 15:45 | Author(s): J.M. Ko
- Abstract
Background:
Two-dimensional CT measurement considered unreliable in the evaluation of small pulmonary nodule less than 2 cm, and a nodule less than 1 cm in diameter considered non-measurable according to RECIST criteria. The aim of this study was to determine the accuracy of visual assessment on the growth of immeasurable small pulmonary nodules less than 1 cm in diameter on CT.
Methods:
We selected 125 CT images (1-mm slice thickness axial images, lung window setting, lung algorithm) which have a small pulmonary nodule less than 1cm. Then, we magnified the pulmonary nodules to 120% in diameter using the Photoshop. We coupled these images to 125 sets of ingrowth and growth groups, respectively. Four radiologists with varying experience read these sets to five-point scale using visual assessment (definitely ingrowth, probably ingrowth, possibly growth, probably growth, and definitely growth).
Results:
The areas under the receiver-operator characteristic curves of visual assessment on growth of small pulmonary nodules were 0.975 for observer 1, 0.986 for observer 2, 0.989 for observer 3, and 0.913 for observer 4, respectively. Sensitivities were 96.0% (120/125), 98.4% (123/125), 98.4% (123/125), and 88.0% (110/125), respectively. Specificities were 99.2% (124/125), 99.2% (123/125), 98.4% (124/125), and 96.8% (121/125), respectively.
Conclusion:
Visual assessment showed high diagnostic performance for determining growth of non-measurable target pulmonary nodules with 20% increase in diameter.
