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J. Zhang
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P1.03 - Poster Session with Presenters Present (ID 455)
- Event: WCLC 2016
- Type: Poster Presenters Present
- Track: Radiology/Staging/Screening
- Presentations: 2
- Moderators:
- Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)
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P1.03-011 - Clinical Characters of 19 Bronchial Asthmatic Patients with Lung Cancer (ID 5562)
14:30 - 15:45 | Author(s): J. Zhang
- Abstract
Background:
To investigate the clinical features of lung cancer among asthmatic patients.
Methods:
Retrospectively analyzed the clinical characteristics of 19 patients with bronchial asthmatic and lung cancer that were treated by the second hospital of Jilin university from 2009 to 2015.
Results:
The morbidity of lung cancer in bronchial asthma patients accounted for 1.4% of the patients in our hospital. All patients were older than 40 years old, among which 11 (58%) were over 60. Cough and expectoration were the major clinical symptoms which occurred in 14 cases(74%). According to the pathological results, 4 cases were squamous cell carcinoma(21%), 7 were small cell carcinoma(37%), 7 wereadenocarcinoma(37%), and only 1 case were poorly differentiated non-small cell carcinoma(5%). In the small cell lung cancers, the primary cancer in 5 cases were still at limited stage, in 2 cases had developed into a extensive tumor. In non small cell lung cancers, there were 2 cases at stage II, 2 cases at stage Ⅲa, 7 cases at stage Ⅲb and 1 cases at stage IV. From the chest CT performance, the patchy and mass like nodules were recognized as the main manifestations. In all the 19 patients, manifestations of asthma were not effectively managed. In 10 of the patients, the PS score was poor and did not receive any anti tumor treatment,while other 9 cases received anti tumor therapy.
Conclusion:
Bronchial asthma, especially those being not well controlled, is a potential risk factor for lung cancer., Lung cancer should be awared in the acute episode of asthma. For asthma exacerbation in patients over 60 years old, the chest CT scan is a recommended choice, or regularly reviewed by low dose CT screening to discover lung cancer at early stage and improve prognosis. But the anti tumor therapy of severe asthma combined with lung cancer patients is still a difficult problem.
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P1.03-057 - Assessment of Lung Cancer Risk- Regional Respiratory Disease Screening Report in Jilin, China (ID 5658)
14:30 - 15:45 | Author(s): J. Zhang
- Abstract
Background:
Both morbidity and mortality of lung cancer ranks first in China. According to the "2012 cancer registration report of China", Northeast China is a high prevalence area of lung cancer, so early diagnosis of lung cancer is particularly important. Based on this, we made the regional survey in Changchun city. (1) To investigate the incidence of pulmonary nodules and lung cancer in Changchun city. (2)To provide the foundation of large data study on early screening of lung cancer and disease control.
Methods:
Carry out the investigation of the people over 50 years of age in 10 communities in Changchun of Jilin Province (A total of 1461 people), including questionnaire, pulmonary function tests and low-dose spiral CT examination. The disease assessment and patient management are based on “Diagnosis and treatment of pulmonary nodules in Chinese expert consensus”.
Results:
The percentage of lung disease in the investigated population was 25.67%, and the constitution of the lung disease included: 30.67% of the lung nodules, 37.07% of chronic obstructive pulmonary disease, 18.67% of inflammation, 5.6% of the lung, 2.13% of pulmonary interstitial fibrosis, 2.13% of pleural effusion and 3.73% of other lung diseases. The number of pulmonary nodules was 115, accounting for 7.87% of the total number of screening, 89 cases of solitary nodules, 26 cases of multiple nodules. A total of 4 patients with lung cancer were confirmed by pathology, including 2 cases of adenocarcinoma, 1 cases of squamous cell carcinoma and 1 case of mucinous carcinoma of the lung. All of the cancer cases were solitary nodules, and accounted for 3.48% of the total samples. Among them, 3 patients are male with a history of smoking, and 1 is female without any history of smoking. According to the nodule size, the diameters of nodule in 3 cases are greater than 8mm and 1 case is less than 4mm. According to the quality of nodules, 3 cases are solid and mixed nodules, and 1 case is ground-glass opacity.
Conclusion:
(1)Smoking is a risk factor for lung cancer. (2) Solid and mixed character nodules in pulmonary nodules and larger diameter nodules are more likely to develop into cancer, so they should be strengthened management. (3) Low-dose spiral CT is helpful for early diagnosis of lung cancer.
