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T. Kishimoto
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P1.01 - Poster Session with Presenters Present (ID 453)
- Event: WCLC 2016
- Type: Poster Presenters Present
- Track: Epidemiology/Tobacco Control and Cessation/Prevention
- Presentations: 1
- Moderators:
- Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)
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P1.01-013 - Emphysematous Changes and Pulmonary Function for Asbestos-Related Lung Cancer in Japan (ID 3736)
14:30 - 15:45 | Author(s): T. Kishimoto
- Abstract
Background:
Smoking accelerates the incidence of asbestos-related lung cancer. We evaluated emphysematous changes by chest CT and pulmonary function for asbestos-related lung cancer in Japan.
Methods:
Two hundred and twenty-two patients of asbestos-related lung cancer compensated by Japanese compensation law were evaluated as age, gender, smoking index, histology, survival, therapy and occupational history including first asbestos exposed age, asbestos exposing terms and latency from the first asbestos exposure to lung cancer． Radiographic evaluation was done by chest CT using Goddard classification of emphysema. Pulmonary function test was done by spirometry and flow-volume curve.
Results:
Ages range from 49 to 92 years with a median of 75 years. Male occupied 97.7%. Non-smoker is only 13 patients and other 209 are smokers with Brinkman Index ranges from 45 to 3000 of a median of 900. For histology of lung cancer, 60.4% are adenocarcinoma and 22.4% of squamous cell carcinoma, 12.6 %of small cell carcinoma and 1.8 of large cell carcinoma and 2.6 % of pleomorphic carcinoma et al. Eighty seven patients were operated and other 87 patients performed chemotherapy. Best supportive therapy is 34 patients. Median survival was 15.8 months. For asbestos histories, median first exposed age was 23 years, asbestos exposing term was 32 years and the latency of lung cancer was 50 years. For Goddard score of emphysematous changes, 28% showed 0 point and 33% of 1~4 points and more than 21 points occupied only 4%, which means very low percentages of emphysematous changes for these asbestos-related lung cancer, nonetheless of high percentages of heavy smokers. For pulmonary function test, FEV1.0% is 70.5%±11.3% and %FEV1.0 is 85.6±22.2%. More than half patients are normal pulmonary function except more than 1,000 of Brinkman index or more than 15 points of Goddard score. From the classification of GOLD criteria, 54.1% are normal, stage 1 is 20.7%, stage 2 is 22.5 % stage 3 is 1.8% and stage 4 is only 0.9%.
Conclusion:
Almost all of asbestos-related lung cancer in Japan are heavy smoker, but 61% showed none or low grade of emphysematous changes by chest CT and only 2.7% had severe pulmonary dysfunction.
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P3.03 - Poster Session with Presenters Present (ID 473)
- Event: WCLC 2016
- Type: Poster Presenters Present
- Track: Mesothelioma/Thymic Malignancies/Esophageal Cancer/Other Thoracic Malignancies
- Presentations: 1
- Moderators:
- Coordinates: 12/07/2016, 14:30 - 15:45, Hall B (Poster Area)
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P3.03-051 - Establishment of Consultation System for Mesothelioma Diagnosis Using Remote Medicine by Internet (ID 4994)
14:30 - 15:45 | Author(s): T. Kishimoto
- Abstract
Background:
In spite of decreased number of mesothelioma in western developed countries, most of Asian countries have still shown an increasing of mesothelioma cases, however it is supposed that in those countries the diagnosis as mesothelioma has not been reached to the level in western countries. Therefore, an improvement of diagnostic accuracy in those Asian countries is necessary. On the contrary, the pathological and/or radiological imaging diagnosis of mesothelioma is a comprehensive matter and the experiences of diagnosis are based on accurate diagnosis. Accordingly, the consultation of diagnosis to other specialists is important. Recent progresses of ICT are conspicuous, and the transmitted radiological imaging and/or pathological figures by means of an optical fiber or Internet are available as routine diagnosis.
Methods:
We have established LOOKREC[®] system for remote imaging and pathological diagnosis. This system consists of several steps on pathological diagnosis as following: scanning of glass slides, transmission of virtual slide to cloud system by Internet, observation of virtual slide on viewer and making of pathological diagnosis, transmission of pathological diagnosis to the clinicians by Internet. On radiological diagnosis, DICOM data are transmitted and radiological diagnosis is transmitted to the clinicians.
Results:
So far, the introduction of this system has been completed at several major hospitals in Vietnam, Iran, and Mongolia. In Japan, we are now using this system at the consensus meeting in the special diagnostic team of mesothelioma by relief or compensation of patients. We have made the consulting system by consensus meeting on the difficult cases of diagnosis as mesothelioma.
Conclusion:
Near future, this system will be effective on the diagnosis of individual mesothelioma case in some Asian countries. In those countries, the statistics on mesothelioma will be improved gradually.
