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M. Pötschke-Langer
Moderator of
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SC07 - New Challenges for Lung Cancer: Waterpipes and E-Cigarettes (ID 331)
- Event: WCLC 2016
- Type: Science Session
- Track: Epidemiology/Tobacco Control and Cessation/Prevention
- Presentations: 3
- Moderators:M. Pötschke-Langer, M. Neuberger
- Coordinates: 12/05/2016, 16:00 - 17:30, Stolz 2
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SC07.01 - Carcinogen Exposure from Waterpipe and ENDS (Electronic Nicotine Delivery Devises) (ID 6625)
16:00 - 17:30 | Author(s): A. Shihadeh
- Abstract
Abstract not provided
Information from this presentation has been removed upon request of the author.
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SC07.02 - Health Effects of E-Cigarette Aerosol and Nicotine Exposure on the Respiratory System (ID 6626)
16:00 - 17:30 | Author(s): C. Pisinger
- Abstract
- Presentation
Abstract not provided
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SC07.03 - Connections of Nicotine to Cancer and its Influence on Cancer Treatment (ID 6627)
16:00 - 17:30 | Author(s): S.A. Grando
- Abstract
- Presentation
Abstract:
There is a growing evidence of direct contributions of nicotine to cancer onset and growth. The list of cancers reportedly connected to nicotine is expanding and presently includes small-cell and non-small-cell lung carcinomas, as well as head and neck, gastric, pancreatic, gallbladder, liver, colon, breast, cervical, urinary bladder and kidney cancers. The mutagenic and tumour-promoting activities of nicotine may result from its ability to damage the genome, disrupt cellular metabolic processes, and facilitate growth and spreading of transformed cells. The nicotinic acetylcholine receptors (nAChRs), which are activated by nicotine, can activate several signaling pathways that can have tumorigenic effects, and these receptors might be able to be targeted for cancer therapy or prevention. There is also growing evidence that the unique genetic makeup of an individual, such as polymorphisms in genes encoding nAChR subunits, might influence the susceptibility of that individual to the pathobiological effects of nicotine. The emerging knowledge about the carcinogenic mechanisms of nicotine action should be considered during the evaluation of regulations on nicotine product manufacturing, distribution and marketing.
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Author of
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MTE01 - Strategies to Improve Tobacco Control in Central European Countries (Ticketed Session) (ID 295)
- Event: WCLC 2016
- Type: Meet the Expert Session (Ticketed Session)
- Track: Epidemiology/Tobacco Control and Cessation/Prevention
- Presentations: 1
- Moderators:
- Coordinates: 12/05/2016, 07:30 - 08:30, Schubert 1
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MTE01.01 - Strategies to Improve Tobacco Control in Central European Countries (ID 6538)
07:30 - 08:30 | Author(s): M. Pötschke-Langer
- Abstract
- Presentation
Abstract:
Tobacco use is the single most preventable cause of death and disease, especially of lung cancer. Approximately 1.6 million people in the WHO European Region die of tobacco-related diseases every year and the Region has the highest proportion of deaths (16%) attributable to tobacco use. Globally, Europe also has the highest prevalence of tobacco smoking among adults (28%), including one of the highest smoking prevalence rates among women (19%). In the meantime it is wellknown that a wide range of political decisions can stop the tobacco epidemic and reduce substantially smoking. According to the first health treaty in history, the WHO Framework Convention on Tobacco Control, following strategies are the most effective: raising cigarette prices through higher cigarette taxe and combating illicit trade of cigarettes, protecting from secondhand smoke through comprehensive smoke-free air laws, enforcing bans on advertising, promotion and sponsorship, placing warnings (pictures and text as big as possible) on tobacco packages and communicate the warnings through media/educational programmes and finally offering greater access to smoking cessation services. WHO Europe has established a database on countries of the WHO European region showing the effects of the reduction in smoking prevalence as a result of implementing tobacco control policies. This presentation will analyse the current situation in this Region and showing the lessons learnt from past years with regards to future prevention of smoking.
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