Virtual Library

Start Your Search

G. Rojas



Author of

  • +

    P1.01 - Poster Session/ Treatment of Advanced Diseases – NSCLC (ID 206)

    • Event: WCLC 2015
    • Type: Poster
    • Track: Treatment of Advanced Diseases - NSCLC
    • Presentations: 1
    • +

      P1.01-028 - Pathological Characteristics of Lung Cancer Patients in Colombian Coffe Zone (ID 3147)

      09:30 - 17:00  |  Author(s): G. Rojas

      • Abstract
      • Slides

      Background:
      During 1998 and 2013 at the “Colombian Coffee Zone” (conformed by three states Caldas, Quindio, and Risaralda) had an increase of 105 mortality cases of Bronchi and lung malignant tumors, as reported in death certificates.

      Methods:
      This is an observational, descriptive study, that was made in patients at Clínica Oncologos del Occidente in the year 2014. Information was taken from the Clinical History Administration System (SAHICO). Thereafter, pending data was collected, by phone calls to patients or patient’s family, according to every case. Patients were interviewed to know their actual performance status and, in case of death, date and basic cause of death was asked

      Results:
      SAHICO reported 178 patients with lung cancer. From these patients, 33 did not have a correct diagnosis. Basically, they did not have a histology report. This happens in patients that consulted with a clinical presentation compatible with a pulmonary origin neoplasia and radiologist reports concluding thorax tumors, which had a lung dependency. But patients had a very low performance status, because they did not assist to the second appointment or never started treatment; finally they died by the disease. The prevalence of these tumors was slightly more common in men. 50% of the patients were between 60.7 and 74 years old. The median age was 69.1 years for males and 64.1 for women. This age median differences were statistically significant (F=9,121 p value=0,003). Also, 90.8% of the patients were from urban areas. 85.3% of tumors treated during 2014 corresponded to NSCLC, meanwhile 10% were Small Cell lung cancer. It was also observed a relationship of 1.7 patients with Squamous cellular carcinoma for every patient with Adenocarcinoma. 28 patients were tested for the EGFR mutation analysis, from these, 5 were mutated. Squamous cellular carcinoma patients were older than Adenocarcinoma patients. Besides this, patients with Small cell had a Media and Median age higher than the squamous cellular carcinoma. Although, Squamous cellular tumor patients were more frequent, the median survival time was inferior to adenocarcinoma patients and the Non-Small cell lung cancer. And neuroendocrine tumor patients had also a longer survival than Squamous cellular patients.

      Conclusion:
      Pathological characteristics of Lung cancer patients in Colombian Coffee Zone are in general similar than the other latitudes, predominating the squamous cellular carcinoma and with an incidence around 10% of the small cell carcinoma; it is striking the sex relationship close than 1:1, presumably for the early incorporation of the female population to smoking habit and to others known risk factors like the expose to combustion biomass smoke. The epidermic growth factor receptor (EGFR) mutation was observed in same proportion than in other studies.

      Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.

  • +

    P2.01 - Poster Session/ Treatment of Advanced Diseases – NSCLC (ID 207)

    • Event: WCLC 2015
    • Type: Poster
    • Track: Treatment of Advanced Diseases - NSCLC
    • Presentations: 1
    • +

      P2.01-031 - Characteristics of Squamous Cellular Carcinoma Patients In 'Colombian Coffee Zone' (ID 3137)

      09:30 - 17:00  |  Author(s): G. Rojas

      • Abstract
      • Slides

      Background:
      During 1998 and 2013 the “Colombian Coffee Zone” (conformed by Caldas, Quindio, and Risaralda states) had an increase of 105 mortality cases of Bronchi and lung malignant tumors, as reported in death certificates.

      Methods:
      This is an observational and descriptive study that was made in patients at Clinica Oncologos del Occidente in the year 2014 and the Information was taken from the Clinical History Administration System (SAHICO). Thereafter, pending data was collected, by phone calls to patients or patient’s family, according to every case. Patients were interviewed to know their actual performance status and, in case of death, date and basic cause of death was asked.

      Results:
      SAHICO reported 178 patients with lung cancer. From these patients, 33 did not have a correct diagnosis. Basically they did not have histology report. There were 130 patients with Non-Small Cell Lung Cancer and Small Cell Lung Cancer. The frequency of lung cancer was slightly more common in men; most of the patients were from Risaralda, followed by Caldas. 50% of the patients were 60.7 to 74 years old. The median age for men was 69.1 years old, and 64.1 years old for women. These median ages differences were statistically significant (F=9,121 p value=0,003). And 90.8% of the patients were from urban areas. 85.3% of tumors treated in 2014 correspond to NSCLC, meanwhile 10% were Small Cell lung cancer. Patients who received radiation therapy had a longer survival than patients without any radiations treatment. The survival media in the radiotherapy group was 180.4 days, and 113.2 days for the group without radiation therapy. This difference was significant (Log Rank test: 4.74, p value 0.029). Only 2 patients had both surgery and radiotherapy and had the major survival time, with a media of 331 days. The mean age of the squamous cellular carcinoma patients was 69.8 years old in 64 patients. It was reported a median survival of 120 days with a confidence interval between 78 and 162 days. Only 8 patients with squamous cellular carcinoma had surgery and reported an increase in their survival time. The time median of survival for the surgical patients was 270 days. Meanwhile, this indicator decreased in the non-surgical patients to 109.9 days.

      Conclusion:
      In general, characteristics of lung squamous cellular carcinoma patients in the Coffee area of Colombia are similar than other regions of the world; incidence in men is only slightly greater than in women, presumably by the early age to start of smoke of the female population and the expose since childhood to others risk factors like biomass combustion smoke. Is clear that patients are detected in an advance stage of disease which has strong influence in prognosis and outcome. Highlights the importance of an integral treatment including all management alternatives and a multidisciplinary equipment of attention for modification of prognosis and survival.

      Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.

  • +

    P3.01 - Poster Session/ Treatment of Advanced Diseases – NSCLC (ID 208)

    • Event: WCLC 2015
    • Type: Poster
    • Track: Treatment of Advanced Diseases - NSCLC
    • Presentations: 1
    • +

      P3.01-027 - Lung Adenocarcinoma in Patients from the Colombian Coffee Zone (ID 3087)

      09:30 - 17:00  |  Author(s): G. Rojas

      • Abstract

      Background:
      During 1998 and 2013 the “Colombian Coffee Zone” (conformed by Caldas, Quindio, and Risaralda states) had an increase of 105 mortality cases of Bronchi and lung malignant tumors, as reported in death certificates.

      Methods:
      This is an observational and descriptive study that was made in patients at Clinica Oncologos del Occidente in the year 2014 and the Information was taken from the Clinical History Administration System (SAHICO). Thereafter, pending data was collected, by phone calls to patients or patient’s family, according to every case. Patients were interviewed to know their actual performance status and, in case of death, date and basic cause of death was asked.

      Results:
      SAHICO reported 178 patients with lung cancer. From these patients, 33 did not have a correct diagnosis. Basically, they did not have a histology report. This happens in patients that consulted with a clinical presentation compatible with a pulmonary origin neoplasia and radiology reports concluding in thorax tumors, which had a lung dependency. But such patients had a very low performance status, because they did not assist to the second consult, they never started treatment, and finally because they died. Among these 178 patients 3 had other diagnoses, which initially were unclear: one had Gastric Cancer, the second had prostate carcinoma and the last one had breast cancer. Also, 12 Patients came with the diagnosis of Adenocarcinoma or Squamous cellular lung cancer, they only went to radiation treatment with us and the rest of the clinical treatment was taken in another clinic, or they died before treatment initiates, this group was called without following. There were 38 patients with adenocarcinoma. The proportion between Squamous Cellular and Adenocarcinoma was 1.7 patients with squamous cellular carcinoma for every patient with Adenocarcinoma. 28 patients were tested for the EGFR mutation analysis, from these, 5 had the EGFR mutation. The average age of the patients with adenocarcinoma was 64.2 years old. The median survival time found was 167.6 days and the calculation for confidence interval of 95% (CI~95%~ 67.3 to 267.9)

      Conclusion:
      Of the population evaluated, proportion of lung adenocarcinoma (ratio of tumors), is different than other reports of the world. Outcome is like patients with another tumors, because they consult to late, in advance stage of disease, then mortality is higher and shorter survival. Implementation in diagnosis of detection of epidermic growth factor receptor mutation (EGFR) in the institution has been of great value to reorient pharmacological treatment.​