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M.O. Tagbarha



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    P1.01 - Poster Session/ Treatment of Advanced Diseases – NSCLC (ID 206)

    • Event: WCLC 2015
    • Type: Poster
    • Track: Treatment of Advanced Diseases - NSCLC
    • Presentations: 1
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      P1.01-026 - Post-Treatment Effects of Lung Cancer on Spinal Fracture (ID 147)

      09:30 - 17:00  |  Author(s): M.O. Tagbarha

      • Abstract

      Background:
      Studies have shown the relationship between cancers and bone diseases. Observations have also shown that the spine, rib and pelvis are more susceptible to cancer for riches in marrow that fosters tumor growth. We particularly examined the relationship with spinal fractures and cancer

      Methods:
      The medical records of more than 100 lung cancer survivors were assessed from six Teaching Hospitals in Eastern (Ethiopia and Tanzania) and Southern African countries from 2003-2013. We checked for osteolytic lesions and osteoblastic lesion as the patients have undergone several kinds of screening during and after cancer treatment including DXA (Dual-energy X-ray Absorptiometry), plain X-ray or magnetic resonance imaging (MRI) to screen for metastatic bone disease

      Results:
      We found that an estimated 30-40% of the lung cancer patients developed bone metastases and disrupted the balance between bone breakdown and repair which caused reduction of bone in some areas and increased density in others. As a result, the bone was weakened and became more prone to spinal fracture after treatment

      Conclusion:
      As lung cancer has spread thereby causing spinal fractures, treatment needs to be focused on disease control with chemotherapy. The treatment of bone metastases will be primarily dependent on an effective treatment against lung cancer itself

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    P2.05 - Poster Session/ Prevention and Tobacco Control (ID 216)

    • Event: WCLC 2015
    • Type: Poster
    • Track: Prevention and Tobacco Control
    • Presentations: 1
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      P2.05-002 - The Risk of Lung Cancer among Women Who Start Smoking as Teenagers (ID 138)

      09:30 - 17:00  |  Author(s): M.O. Tagbarha

      • Abstract

      Background:
      To examine the effect of smoking on lung cancer risk in a large population-based cohort of women, many of whom started smoking as teenagers

      Methods:
      We followed 102,098 women, ages 30 to 50 years, completing a mailed questionnaire at recruitment to the Nigerian-Ethiopian Cohort Study in 2011/2012, through December 2013. We used Cox proportional hazard regression models to estimate relative risk (RR) of lung cancer associated with different measures of smoking initiation, duration, and intensity adjusting for confounding variables. We conducted analyses on the entire study population, among women who had smoked for at least 20 years, among non drinkers, and separately for each country

      Results:
      Altogether, 1,240 women were diagnosed with incident, invasive lung cancer. Compared with never smokers, women who smoked for at least 20 years and who smoked 10 cigarettes or more daily had a RR of 1.34 (95% CI, 1.06-1.70). Likewise, those who initiated smoking prior to their first birth (1.27, 1.00-1.62), before menarche (1.39, 1.03-1.87), or before age 15 (1.48, 1.03-2.13) had an increased risk. The increased RR associated with smoking was observed among nondrinkers of alcohol, women with and without a family history of lung cancer, pre-menopausal and post-menopausal women, and in both countries

      Conclusion:
      Our results support the notion that women who start smoking as teenagers and continue to smoke for at least 20 years have increased lung cancer risk

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    P3.05 - Poster Session/ Prevention and Tobacco Control (ID 217)

    • Event: WCLC 2015
    • Type: Poster
    • Track: Prevention and Tobacco Control
    • Presentations: 1
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      P3.05-003 - Beliefs, Attitudes and Treatment Access to Lung Cancer amongst Nigeria Rural Men (ID 139)

      09:30 - 17:00  |  Author(s): M.O. Tagbarha

      • Abstract

      Background:
      Evidences of lung cancer cases from scientific researches have being on the rise in the last few decades and tobacco which is a major risk factor causes about 90% of cancer diagnosed around the world. The need to reduce this scourge has become more important

      Methods:
      An interview guide was designed specifically for these studies in which 1500 rural men in Nigeria most of which were age 35 and over took part in. It contained questions about beliefs, orientation, knowledge, understanding and attitudes about Lung Cancer Diagnosis and incidences. In addition, questions assessing the variables of the Health Belief Model and health motivations also were included. The data were obtained during face-to-face interviews in the primary language of the participating people. The interviews were translated into English

      Results:
      Out of the 1500 men who participated, only 10% of the participants knew about lung cancer, 5% had undergone at least one Lung Cancer Diagnosis during their lives, and 85% were not aware of the disease. There was little or no access to treatment even at early detection in these rural areas thereby causing vulnerability to loss of life. Majority of these men (95%) said they knew little or nothing about lung cancer. While 10% of the men said detecting cancer early was important, only 5% reported that cancer could be cured. Age, education, or mother tongue showed no statistically significant relationship with the lung health practice scores. However, proficiency with the English language (p = 0.009) and number of years exposed to awareness and education (p = 0.009) had a significant relationship with the lung health practice scores. The significant explanatory factor for the variable lung health practices was a cue to action (p = 0.009)

      Conclusion:
      The level of awareness and treatment access to lung cancer amongst Nigeria’s rural men is extremely low thereby making them not to engage in screening and/or detection practices. This alarming situation calls for urgent intervention of medical/health organizations to provide immediate lung cancer awareness, diagnosis and care so as to reduce incidences or threat at early detection. Tobacco which is known as a major cause of cancer (90%) is widely used by these rural men thereby making them so vulnerable. Awareness is suggested while providing smoking cessation for smokers who intend to quit