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P. Martin



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    MTE24 - Treatment of Cachexia Over the Next Five Years (ID 68)

    • Event: WCLC 2013
    • Type: Meet the Expert (ticketed session)
    • Track: Supportive Care
    • Presentations: 1
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      MTE24.1 - Treatment of Cachexia Over the Next Five Years (ID 622)

      07:00 - 08:00  |  Author(s): P. Martin

      • Abstract
      • Presentation
      • Slides

      Abstract
      Treatment of Cancer Cachexia over the next 5 years. The focus of this session will be on the emerging evidence for therapeutic approaches, outside anti-cancer treatments, that help clinicians care for patients and their families with anorexia cachexia syndrome. An overview of the basic pathophysiology will be presented to enable understanding of the diverse interventions studied as well as those that are currently under investigation. The challenge and importance of defining the syndrome will be discussed. It will also be important to discuss the drivers that are moving the sector towards the concept of categorising patients into pre-cachexia, established cachexia and refractory cachexia. This has implications about when to intervene and how the goals of interventions may change over time. This may help design better matched cohorts for clinical trials, influence design of service models and alert us to the possibility of previous false negative studies. There will be a review of the prevalence of anorexia cachexia in various tumour streams and at different time points over the illness trajectory. The scope and scale of the clinical impact will be discussed in detail including the potential importance of symptom clusters, association with total symptom burden, links to fatigue and the evolving picture of the psycho-social distress that is common for suffers and their families or carers. Significant time will be dedicated to summarising the evidence base for pharmacological, nutritional and exercise approaches. The author will share his own experience in leading a dedicated inter-disciplinary cancer cachexia clinic over the last 9 years in Victoria and why he feels a multi-modality approach should be adopted. Lastly an outline of what might represent best practice for the management of this syndrome over the next five years will be presented for open discussion.

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