Author of

• 10946

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  P1.19 - Poster Session 1 - Imaging (ID 179)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Imaging, Staging & Screening
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/28/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

  • 10959

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    P1.19-013 - FDG-PET/CT differ Bronchial NETs from hamartomas (ID 3363)

    09:30 - 16:30  |  Author(s): O. Grundberg
    • Abstract

    Background
    Bronchial NET:s account for approximately 1% of all lung cancers and usually require surgical removal. Hamartoma is a benign tumor not necessary to treat. The two conditions may have a very similar radiological appearance when studied by chest x-ray or CT, especially when the bronchial NET has a peripheral location. The objective was to assess if integrated FDG PET-CT examination could contribute to the decision-making process.

    Methods
    The material consists of 119 consecutively operated patients at our Centre during the Period of October 2005 to February 2012, where the Diagnosis (pathologically confirmed) either was Hamartoma or bronchial NET. Retrospective analysis of the Patient Charts and Radiology were performed. Out of these 119 cases, 58 hamartomas and 38 bronchial NET:s had been subject to FDG-PET-CT. All examinations were reviewed by one single radiologist/nuclear medicine physician. SUV-values were measured as well as morphological characteristics were assessed.

    Results
    Of the 38 Bronchial NET:s, 23 were peripheral and 8 central according to radiological appearance. Mean SUVmax of the Bronchial NET:s was 3.5 ( range 0–7.5). 6 Bronchial NET:s did not show any FDG-uptake. Mean SUVmax of the hamartomas was 0.77 (range 0.0–3.7). 31 of the hamartomas (61%) showed no FDG-uptake.

    Conclusion
    Although peripheral Bronchial NET:s may be indistinguishable to hamartoma at CT, the two conditions differ in FDG-PET appearance. Thus, it may be possible to avoid unnecessary thoracotomy when a peripheral solid lesion shows absence of FDG-uptake.