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  • ACLC 2018

    IASLC Asia Conference on Lung Cancer 2018

    Access Abstracts and Powerpoint Slides to select presentations that took place during the IASLC Asia Conference on Lung Cancer 2018 in Guangzhou, China from November 8 - 10, 2018. This package is available for no charge to active IASLC Members.

    Presentation Date(s):  
    • November 8 - 10, 2018
    • Total Presentations: 137

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    Poster Session

    • Type: Poster Session
    • Track:
    • Presentations: 90
    • Coordinates: 11/07/2018, 00:00 - 00:00, Poster Hall
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      P001 - Discrepancy of Oncogenic Mutations in Bone Metastasis Derived from Lung Adenocarcinoma

      00:00 - 00:00  |  Author(s): L. Huang

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      P002 - Surgical Resection Improves the Survival of

      00:00 - 00:00  |  Author(s): B. Zhang

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      P003 - Prognosis of Advanced Lung Cancer by Age Groups : A SEER Database Analysis

      00:00 - 00:00  |  Author(s): B. Wang

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      P006 - Evaluation of Efficacy and Safety of Uniportal Segmentectomy in the Treatment of Small Lung Nodule

      00:00 - 00:00  |  Author(s): C. Zhang

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      P008 - Correlation Between Genetic Mutation State and Cancer-Associated Thrombosis in Advanced Cancer Patients

      00:00 - 00:00  |  Author(s): X. Zhang

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      P011 - Concurrent ALK/EGFR Alterations in Chinese Lung Cancers: Frequency, Clinical Features, and Differential Response to Therapy

      00:00 - 00:00  |  Author(s): D. Wu

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      P012 - Pooled Safety Analysis for Two Generations ALK Inhibitors: A Meta Analysis

      00:00 - 00:00  |  Author(s): D. Sun

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      P013 - Anti-PD-1 Combination

      00:00 - 00:00  |  Author(s): F. Zhang

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      P015 - Motion Management Without Fiducial Tracking Using Cyberknife SBRT

      00:00 - 00:00  |  Author(s): G. Lohith

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      P016 - The Optimal ALK inhibitor in Advanced ALK-Positive NSCLC Patients: An Indirect Comparison Between Brigatinib and Alectinib

      00:00 - 00:00  |  Author(s): H Zhou

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      P017 - Investigation of Mediastinal Lymph Node Metastasis in Non-Small Cell Lung Cancer

      00:00 - 00:00  |  Author(s): G. Wang

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      P018 - Afatinib Named Patient Use Program in Advanced NSCLC with Progression on Prior Therapy: Experience from Asian Centers

      00:00 - 00:00  |  Author(s): G. Chang

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      P020 - Characterization of Met Exon 14 Skipping and Association with Clinical Outcomes of Crizotinib in Chinese Lung Cancers

      00:00 - 00:00  |  Author(s): H. Yang

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      P021 - The Impact of TP53 Mutation and Tumor Mutation Number on Outcomes in Patients with Stage I Non

      00:00 - 00:00  |  Author(s): S. Zheng

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      P022 - Association Between Oral Leukoplakia and Lung Cancer: A 28-Year Follow-Up Study in the Linxian General Population Trial

      00:00 - 00:00  |  Author(s): H. Liang

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      P023 - Factors associated with administration of subsequent cytotoxic chemotherapy after nivolumab in patients with advanced NSCLC

      00:00 - 00:00  |  Author(s): H. Jo

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      P024 - Sleeve Lobectomy for Centrally Located Non-Small Cell Lung Cancer: Experience of a Single Institute

      00:00 - 00:00  |  Author(s): H. Liu

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      P025 - Which Is the Optimal Immunotherapy for Advanced Non-Squamous Non-Small-Cell Lung Cancer in Combination with Chemotherapy?

      00:00 - 00:00  |  Author(s): H Zhou

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      P026 - Impact of Prior Cancer History on the Overall Survival of Younger Patients with Lung Cancer

      00:00 - 00:00  |  Author(s): H. Zhou

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      P028 - A Novel Method for Detecting Surface PD-L1 on Circulating Tumor Cells in Peripheral Blood of Patients with SCLC

      00:00 - 00:00  |  Author(s): D. Zhao

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      P029 - Circulating MDSCs Derived from Small Cell Lung Cancer Patients Secrete TGF - Beta 1 and Play Roles in Angiogenesis

      00:00 - 00:00  |  Author(s): S. Lan

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      P030 - Prognostic Factors for Advanced Lung Adenocarcinoma Patients Who Received Tyrosine Kinase Inhibitor and Radiotherapy

      00:00 - 00:00  |  Author(s): H. Yang

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      P032 - Integrin Subunit Alpha 5: Potential Prognostic Biomarker in Lung Adenocarcinoma

      00:00 - 00:00  |  Author(s): J.H. Hong

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      P033 - A Fusion-Protein Approach Enabling Mammalian Cell Production of Tumor Targeting Protein Domains for Therapeutic Development

      00:00 - 00:00  |  Author(s): J. Hu

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      P034 - A Case of Stage IIIA Thymoma Underwent Thymectomy with the Subxiphoid Approach

      00:00 - 00:00  |  Author(s): B. Aramini

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      P036 - Rechallenge Pemetrexed-Based Chemotherapy Provides an

      00:00 - 00:00  |  Author(s): J. Wang

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      P037 - QSOX1/2 Regulates

      00:00 - 00:00  |  Author(s): Y. Li

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      P038 - Docosapentaenoic Acid and Lung Cancer Risk: A Mendelian Randomisation Study

      00:00 - 00:00  |  Author(s): J. Liu

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      P039 - Clinical Characteristics and Survival of Patients with Lymphoepithelioma-Like Carcinoma in Lung and Bronchus and Other Sites

      00:00 - 00:00  |  Author(s): J. Liu

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      P040 - Highly Sensitivity and Fast Genetic Diagnosis by Mean of a Novel NGS-Based Resequencing Gene Panel Underlying SCLC Patients

      00:00 - 00:00  |  Author(s): J. Wang

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      P041 - Different Recurrence Models in Lung Cancer Patients Between

      00:00 - 00:00  |  Author(s): J. Xia

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      P042 - LincRNA00494 Suppresses Non-Small Cell Lung Cancer Cell Proliferation by Regulating SRCIN1 Expression in A ceRNA Manner

      00:00 - 00:00  |  Author(s): J. Dong

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      P043 - Cost-Effectiveness Analysis of Different Sequences of Osimertinib Administration for EGFR-Mutated Non-Small-Cell Lung Cancer

      00:00 - 00:00  |  Author(s): W. Li

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      P044 - Cost-Effectiveness Analysis of Icotinib vs Whole-Brain Irradiation in NSCLC Patients with Brain Metastases

      00:00 - 00:00  |  Author(s): W. Li

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      P045 - Prognostic Value of MHC-I, PD-L1 and CD8+ TILs Expressions in Patients with Surgically Resected Non-Small Cell Lung Cancer

      00:00 - 00:00  |  Author(s): X. Ding

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      P047 - Clinical Characteristics of the Surviving Lung Cancer Patients at Shanghai Chest Hospital During 2007- 2017

      00:00 - 00:00  |  Author(s): Y. Zhao

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      P049 - Neurocognitive Functions Before Radiotherapy for Brain Metastasis from Lung Cancer: An Analysis of 74 Cases

      00:00 - 00:00  |  Author(s): J. Zhen

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      P050 - Long-Term Survival of Stage IIIA-N2 NSCLC Patients with Interstitial Lung Diseases

      00:00 - 00:00  |  Author(s): J. Watanabe

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      P051 - A Novel

      00:00 - 00:00  |  Author(s): K. Yin

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      P052 - A Biomarker Study of Advanced Non-Small Cell Lung Cancer Using Ultra-High-Performance Liquid Chromatography-Mass Spectrometry

      00:00 - 00:00  |  Author(s): K. Zhang

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      P053 - The Potential of Assessing Blood Tumor Mutation Burden (bTMB) Using a Large Panel

      00:00 - 00:00  |  Author(s): K. Zhang

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      P054 - Applicability of the Lung-molGPA Index in NSCLC

      00:00 - 00:00  |  Author(s): K. Chen

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      P057 - Pembrolizumab +

      00:00 - 00:00  |  Author(s): K.F. Ang

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      P058 - Effects of Neoadjuvant Chemotherapy on the Expression

      00:00 - 00:00  |  Author(s): W. Sun

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      P061 - Real Clinical Practice of Using Immunotherapy In NSCLC Patients With EGFR Mutation

      00:00 - 00:00  |  Author(s): L. Shen

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      P063 - STE029 Overcomes EGFR-TKI Resistance in Human Lung Adenocarcinoma

      00:00 - 00:00  |  Author(s): L. Huang

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      P066 - A Phase I Study of Apatinib Combined with Pemetrexed and Carboplatin in Untreated EGFR-Negative Stage IV Non-Squamous NSCLC

      00:00 - 00:00  |  Author(s): M. Huang

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      P068 - The Geriatric Nutritional Risk Index Predicts the Overall Survival in Geriatric Patients with Metastatic Lung Adenocarcinoma

      00:00 - 00:00  |  Author(s): M. Tang

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      P069 - HOTAIR, A Long Non-Coding RNA, Is a Marker of Abnormal Cell Cycle Regulation in Lung Cancer

      00:00 - 00:00  |  Author(s): M. Liu

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      P070 - Pembrolizumab for Non-Small Cell Lung Cancer with Untreated Central Nervous System Metastases: A Case Report

      00:00 - 00:00  |  Author(s): M. Di

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      P071 - Variants Distribution and Heterogeneity of Outcomes to Crizotinib in ALK-Rearranged Chinese Non-Small Cell Lung Cancers

      00:00 - 00:00  |  Author(s): N. Liang

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      P072 - Low Detection Rate of EGFR Driver and T790M Mutation in Plasma by

      00:00 - 00:00  |  Author(s): O. Yuko

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      P073 - Cbl-b Predicts Prognosis of NSCLC Patients and Affects PD-L1 Expression in A549

      00:00 - 00:00  |  Author(s): P. Li

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      P075 - Hippo-YAP Pathway Mediated Resistance to Crizotinib in ROS1-Positive Lung Cancer

      00:00 - 00:00  |  Author(s): P. Sun

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      P076 - A Lung Adenocarcinoma with Concomitant EGFR And De Novo MET Amplification Response Well to Combination of TKI And Bevacizumab

      00:00 - 00:00  |  Author(s): Q. Chu

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      P077 - miR-338-3p Promotes the Resistance of Non-Small Cell Lung Cancers To EGFR-TKI By Targeting PTPN12

      00:00 - 00:00  |  Author(s): Q. Wu

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      P080 - Efficacy and Safety of Docetaxel Plus Ramucirumab: A Consecutive Analysis of 68 Patients with Advanced NSCLC

      00:00 - 00:00  |  Author(s): S. Yokota

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      P081 - Clinical Characteristics and Molecular Patterns Of RET-Rearranged Lung Cancer in Chinese Patients

      00:00 - 00:00  |  Author(s): S. Fei

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      P082 - DNA Methylation: A More Sensitive Marker for Treatment Monitoring?

      00:00 - 00:00  |  Author(s): S. Xia

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      P083 - Efficacy of EGFR-TKIs in Patients Harboring EGFR Mutations with Non-Adenocartinoma Histology

      00:00 - 00:00  |  Author(s): O Yuko

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      P084 - Musashi-2 Expression Is an

      00:00 - 00:00  |  Author(s): T. Wang

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      P086 - Toward the Standardization of Bioinformatics Methods for the Accurate Assessment of Tumor Mutational Burden (TMB)

      00:00 - 00:00  |  Author(s): H. Chang

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      P087 - TNM Staging Inversely Correlates with Age in ALK-positive Lung Cancer

      00:00 - 00:00  |  Author(s): W. Tang

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      P088 - Distribution of Different HER2 Mutations

      00:00 - 00:00  |  Author(s): W Wang

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      P089 - An EGFR KDD Data in the Chinese NSCLC Population and the Response to EGFR-TKIs: A Multicenter Study

      00:00 - 00:00  |  Author(s): W. Wang

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      P090 - Prevalence of Brain Metastases in Limited Stage Small Cell Lung Cancer Immediately Before Prophylactic Cranial Irradiation

      00:00 - 00:00  |  Author(s): X. Chu

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      P091 - Association Between BIM Polymorphism and Lung Cancer Outcomes: A Meta-analysis

      00:00 - 00:00  |  Author(s): X. Li

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      P093 - DNA Methylation in CTC And ctDNA is A Promising Marker for Early Detection of Lung Cancer Metastasis

      00:00 - 00:00  |  Author(s): X. Qiu

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      P094 - Evaluation of the Efficacy of Salvage Surgery for Advanced NSCLC Patients After Neoadjuvant

      00:00 - 00:00  |  Author(s): X. Cao

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      P095 - MicroRNA-330-3p Promotes Brain Metastasis of Non-Small Cell Lung Cancer by Activating MAPK/MEK/ERK Signaling Through GRIA3

      00:00 - 00:00  |  Author(s): C. Wei

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      P096 - MLPH Activates CDC42/PAK1 Signaling to Promote Epithelial

      00:00 - 00:00  |  Author(s): C. Wei

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      P097 - ctDNA Changes and TCR Diversity Associated with Clinical Outcomes Following Brain Therapy in NSCLC

      00:00 - 00:00  |  Author(s): C. Wei

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      P100 - Stem Cell Factor Leads to Lung Cancer Escapes from Anti-Angiogenic Therapy by Increasing the ALDH1+ Lung Cancer Cell Number

      00:00 - 00:00  |  Author(s): Y. Liu

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      P101 - Intratumor Heterogeneity Comparison Among Different Subtypes of

      00:00 - 00:00  |  Author(s): Y. Zhang

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      P102 - The Correlations of Tumor Mutational Burden Among Single-region Tissue, Multi-region Tissues And Blood in NSCLC

      00:00 - 00:00  |  Author(s): Y. Zhang

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      P104 - Anti-PD-1 Combination Therapy in Second or Later Lines in

      00:00 - 00:00  |  Author(s): F. Zhang

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      P105 - Computational Design of IgG-like Tetra-specific Antibody Targeting EGFR/VEGF/PD-1/CTLA-4 Against NSCLC

      00:00 - 00:00  |  Author(s): Y. Hu

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      P106 - The Efficacy and Safety of Bevacizumab Combined with Chemotherapy in the Treatment of Drug-Resistant SCLC

      00:00 - 00:00  |  Author(s): X. Liu

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      P107 - The Study of Relationship Between Tumor Burden (TMB) and Molecular Typing of Non-Small Cell Lung Cancer (NSCLC)

      00:00 - 00:00  |  Author(s): R. Zhong

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      P109 - Combined Chemotherapy Versus Topotecan Monotherapy as Second-Line Treatment for Patients with Sensitive Relapsed SCLC

      00:00 - 00:00  |  Author(s): L. Zhang

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      P111 - Circulating Tumor Cells Combined Myeloid Derived Suppressor Cells Predict Prognosis of Advanced Small Cell Lung Cancer

      00:00 - 00:00  |  Author(s): Y. Liu

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      P112 - Significance of Low Expression of Tumor Associated Gene ki67 in Recurrence of Small Cell Lung Cancer

      00:00 - 00:00  |  Author(s): X. Zhang

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      P113 - Icotinib Alone or with Radio Therapy Inpatients with EGFR Mutations Non-Small Cell Lung Cancer Who Develop Brain Metastases

      00:00 - 00:00  |  Author(s): Y. Xin

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      P114 - Whole-Exome Sequencing

      00:00 - 00:00  |  Author(s): Y. Xu

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      P115 - Clinical Outcome of Crizotinib in Diverse ALK Fusion Partners and Different Detection Methods Treatment Na

      00:00 - 00:00  |  Author(s): Y. Zhang

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      P116 - Real World Data of 1st Line A+T in Advanced EGFR+ NSCLC: Clinical Outcome, PFS Influential Factors and Acquired Resistance

      00:00 - 00:00  |  Author(s): Y. Zhang

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      P117 - MET 14 Skipping Mutation in Pulmonary Sarcomatoid Carcinoma Using Reverse Transcription Polymerase Chain Reaction Method

      00:00 - 00:00  |  Author(s): Y. Zhu

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      P119 - Impact of Treatment Modality on Long-Term Survival of Small-Cell Lung Cancer with IA Stage: a Population-based Study

      00:00 - 00:00  |  Author(s): Y. Zheng

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      P120 - How to Become Exsomes As Messengers and Sentinels to Influence Lung Cancer Growing?

      00:00 - 00:00  |  Author(s): Z. Yu

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      P121 - Clinical Value of Local Therapy in Advanced Crizotinib-Treated ALK-Rearranged Lung Cancer: Pattern of Failure Analyses

      00:00 - 00:00  |  Author(s): J. Ni

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    Best abstracts selected from submissions 1

    • Type: Oral Session
    • Track:
    • Presentations: 2
    • Coordinates: 11/08/2018, 10:55 - 11:30, Crystal Ballroom
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      OA01 - LKB1 Pathway Variant TSC2 rs30259 Predicts the Prognosis in Early Stage Non-Small Cell Lung Cancer

      00:55 - 01:05  |  Author(s): S.K. Do

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      OA02 - Targeted Next-Generation Sequencing Reveals Relapse-Associated Genomic Alterations in Early Stage Non-Small Cell Lung Cancer

      01:05 - 01:15  |  Author(s): W. Cho

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    Best abstracts selected from submissions 2

    • Type: Oral Session
    • Track:
    • Presentations: 2
    • Coordinates: 11/08/2018, 16:20 - 17:00, Jade Ballroom
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      OA03 - Afatinib Followed by Osimertinib in Real-World Patients with EGFR Mutation-Positive Advanced NSCLC: The Giotag Study

      06:20 - 06:30  |  Author(s): M.J. Hochmair

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      OA04 - Factors Influencing the Non-Administration of Chemotherapies in Patients Who Progressed After

      06:30 - 06:40  |  Author(s): T. Mizuno

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    Best abstracts selected from submissions 3

    • Type: Oral Session
    • Track:
    • Presentations: 2
    • Coordinates: 11/08/2018, 16:20 - 17:00, Crystal Ballroom 1
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      OA05 - Tumor Mutational Burden Standardization Initiative: Establish a Consistent Methodology for TMB Measurement in Clinical Samples

      06:20 - 06:30  |  Author(s): F Yan

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      OA06 - Tepotinib in Non-Small Cell Lung Cancer with MET Exon 14-Skipping Mutations or MET Amplification:

      06:30 - 06:40  |  Author(s): P. Paik

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    Parallel Session 1 - Biomarker detecting for lung cancer: new technique and new opinion

    • Type: Oral Session
    • Track:
    • Presentations: 3
    • Slides Available
    • Coordinates: 11/08/2018, 16:20 - 17:00, Jade Ballroom
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      What is a trustworthy biomarker? (Slides Available)

      04:25 - 04:50  |  Author(s): C Manegold

      • Abstract
      • Slides

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      Standardization of molecular testing in China (Slides Available)

      04:50 - 05:15  |  Author(s): X Zhang

      • Abstract
      • Slides

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      Discussant - Sequencing or Combination? (Slides Available)

      06:40 - 07:00  |  Author(s): J Hu

      • Abstract
      • Slides

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    Parallel Session 2 - Brain metastases and Leptomeningeal metastasis

    • Type: Oral Session
    • Track:
    • Presentations: 3
    • Slides Available
    • Coordinates: 11/08/2018, 16:20 - 17:00, Crystall Ballroom 1
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      Diagnosis and management of leptomeningeal metastasis (Slides Available)

      05:15 - 05:40  |  Author(s): J Yang

      • Abstract
      • Slides

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      Optimal radiotherapy for CNS metastasis in patients with a driver oncogene (Slides Available)

      20:25 - 20:50  |  Author(s): Y Lu

      • Abstract
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      Can this drug penetrate the brain? (Slides Available)

      20:50 - 21:15  |  Author(s): F Kong

      • Abstract
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    Parallel Session 3 - Tobacco control, Staging and cancer prevention in Asia

    • Type: Oral Session
    • Track:
    • Presentations: 1
    • Slides Available
    • Coordinates: 11/08/2018, 16:20 - 17:00, Crystall Ballroom 3
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      Tobacco control in China (Slides Available)

      04:00 - 04:20  |  Author(s): X Zhi

      • Abstract
      • Slides

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    Plenary Session - Past, Present and Future of Targeted Therapy in NSCLC

    • Type: Oral Session
    • Track:
    • Presentations: 3
    • Slides Available
    • Coordinates: 11/08/2018, 16:20 - 17:00, Crystal Ballroom
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      Optimal sequence of EGFR TKI (Slides Available)

      08:15 - 08:40  |  Author(s): T Mok

      • Abstract
      • Slides

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      Clinical application of ctDNA in management of oncogenic driven lung cancer (Slides Available)

      09:05 - 09:30  |  Author(s): S Lu

      • Abstract
      • Slides

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      Optimal sequence of ALK TKI (Slides Available)

      08:40 - 09:05  |  Author(s): I Ou

      • Abstract
      • Slides

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    Best abstracts selected from submissions 4

    • Type: Oral Session
    • Track:
    • Presentations: 2
    • Slides Available
    • Coordinates: 11/09/2018, 10:50 - 11:30, Crystal Ballroom
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      OA07 - Clinical Characterization Of ERBB2 Exon 20 Insertions and Heterogeneity of Outcomes to Afatinib in Chinese Lung Cancers (Slides Available)

      16:50 - 17:00  |  Author(s): Z. Liu

      • Abstract
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      OA08 - Efficacy and Safety of Sintilimab Combined with 1st Line Chemotherapy in Advanced Squamous Cell Non-small Cell Lung Cancer (Slides Available)

      17:00 - 17:10  |  Author(s): K. Ying

      • Abstract
      • Slides

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    Best abstracts selected from submissions 5

    • Type: Oral Session
    • Track:
    • Presentations: 2
    • Slides Available
    • Coordinates: 11/09/2018, 16:20 - 17:00, Crystal Ballroom 1
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      OA09 - Preliminary Clinical Activity of Repotrectinib (TPX-0005) in Advanced ROS1 Fusion-Positive Non-Small Cell Lung Cancer (Slides Available)

      22:20 - 22:30  |  Author(s): S. Ou

      • Abstract
      • Slides

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      OA10 - CheckMate 078: Patient-Reported Outcomes (PROs) With Nivolumab vs Docetaxel in Advanced Non-Small Cell Lung Cancer (NSCLC)

      06:30 - 06:40  |  Author(s): Y. Wu

      • Abstract

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