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W.E.E. Eberhardt

Moderator of

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    Management of non-oncogene driven NSCLC (ID 11)

    • Event: ELCC 2017
    • Type: Specialty Session
    • Track:
    • Presentations: 4
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      Anti-EGFR therapies in unselected NSCLC patients (ID 43)

      11:00 - 12:30  |  Author(s): L. Paz-Ares

      • Abstract
      • Presentation
      • Slides

      Abstract not provided

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      Elderly and frail patients: Choosing the optimal treatment option (ID 45)

      11:00 - 12:30  |  Author(s): M.J. Ahn

      • Abstract
      • Presentation
      • Slides

      Abstract not provided

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      Second line treatment and beyond: Selecting new agents in the arena for subsequent therapy (ID 44)

      11:00 - 12:30  |  Author(s): L. Horn

      • Abstract
      • Presentation
      • Slides

      Abstract not provided

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      The revival of antiangiogenic therapies (ID 42)

      11:00 - 12:30  |  Author(s): R. Garcia Campelo

      • Abstract
      • Presentation
      • Slides

      Abstract not provided

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    The implications of TNM staging on clinical practice (in NSCLC) (ID 3)

    • Event: ELCC 2017
    • Type: Educational session
    • Track:
    • Presentations: 4
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      Combination of molecular markers and TNM staging to refine prognosis and therapy (ID 10)

      14:30 - 16:00  |  Author(s): M.S. Tsao

      • Abstract
      • Presentation
      • Slides

      Abstract not provided

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      M1b: Will it be useful to establish a new paradigm of oligometastatic disease? (ID 9)

      14:30 - 16:00  |  Author(s): W.E.E. Eberhardt

      • Abstract
      • Presentation
      • Slides

      Abstract not provided

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      Surgical implications (ID 8)

      14:30 - 16:00  |  Author(s): T. Mitsudomi

      • Abstract
      • Presentation
      • Slides

      Abstract not provided

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      The impact on bronchoscopic staging (ID 7)

      14:30 - 16:00  |  Author(s): D. Gompelmann

      • Abstract
      • Slides

      Abstract not provided

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Author of

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    Poster Display Session (ID 63)

    • Event: ELCC 2017
    • Type: Poster Display Session
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 5/07/2017, 12:30 - 13:00, Hall 1
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      125P - Clinical research platform into molecular testing, treatment and outcome of non-small cell lung carcinoma Patients (CRISP): A prospective German registry in stage IV NSCLC, AIO-TRK-0315 (ID 388)

      12:30 - 13:00  |  Author(s): W.E.E. Eberhardt

      • Abstract

      Background:
      Treatment in NSCL is quickly evolving and new agents make it to the routine practice at a rapid pace. Whether outcome and PRO data generated in clinical trials with often narrow inclusion and exclusion criteria will hold up in the routine practice is of high interest, especially due to the increasing costs of new drugs. Therefore, registry data are of ever increasing importance to patients, physicians and reimbursement institutions.

      Methods:
      Therefore, we have started a prospective, clinical registry for patients with metastatic NSCLC. The purpose of CRISP is to set up a national clinical research platform to document representative data on molecular testing, sequences of systemic therapies and other treatment modalities, course of disease in patients with advanced or metastatic NSCLC in Germany not amenable to curative treatment. A particular focus is on molecular biomarker testing of patients before the start of 1[st] -line treatment. The data shall be used to assess the current state of care and to develop recommendations concerning topics that could be improved. PRO assessment will provide large-scale data on quality of life and anxiety/depression for real-life patients in routine practice. In addition, two questionnaires (concerning individual quality of life and patient-caregiver communication) will be validated in German patients with metastatic NSCLC. Furthermore, CRISP will set up a decentral tissue annotation for future collaborative, investigational scientific biomarker testing. This study will be carried out in up to 150 representative cancer centers in all therapeutic sectors in Germany. More than 8000 patients will be recruited and followed up to a maximum of 3 years, respectively until death.

      Results:
      The first patients have been included in Dec. 2015. As of Jan. 2[nd] 2017, 71 centers are recruiting patients and 529 patients have been recruited. Preliminary data will be presented at the meeting for molecular testing, demographic data as well as treatment stratification in the 1[st] line setting.

      Conclusions:
      The registry CRISP will be the first to present representative real life data, covering all treatment settings of patients with NSCLC in Germany.

      Clinical trial identification:
      NCT02622581

      Legal entity responsible for the study:
      AIO-Studien-gGmbH

      Funding:
      CRISP is supported by Grants from AstraZeneca GmbH, Boehringer Ingelheim Pharma GmbH & Co. KG, Bristol-Myers Squibb GmbH & Co. KGaA, Celgene GmbH, Lilly Deutschland GmbH, MSD Sharp & Dohme GmbH, Novartis Pharma GmbH, and Pfizer Pharma GmbH.

      Disclosure:
      All authors have declared no conflicts of interest.

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    SCLC and early stage NSCLC (ID 62)

    • Event: ELCC 2017
    • Type: Proffered Paper session
    • Track:
    • Presentations: 1
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      Invited Discussant 44O, 59O and 60O (ID 545)

      09:00 - 10:30  |  Author(s): W.E.E. Eberhardt

      • Abstract
      • Presentation
      • Slides

      Abstract not provided

      Only Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login, select "Add to Cart" and proceed to checkout. If you would like to become a member of IASLC, please click here.

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    The implications of TNM staging on clinical practice (in NSCLC) (ID 3)

    • Event: ELCC 2017
    • Type: Educational session
    • Track:
    • Presentations: 1
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      M1b: Will it be useful to establish a new paradigm of oligometastatic disease? (ID 9)

      14:30 - 16:00  |  Author(s): W.E.E. Eberhardt

      • Abstract
      • Presentation
      • Slides

      Abstract not provided

      Only Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login, select "Add to Cart" and proceed to checkout. If you would like to become a member of IASLC, please click here.

      Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.