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  P1.11 - Poster Session/ Palliative and Supportive Care (ID 229)

  • Event: WCLC 2015
  • Type: Poster
  • Track: Palliative and Supportive Care
  • Presentations: 1
  • Moderators:
  • Coordinates: 9/07/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)

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    P1.11-009 - Predictors of Hospital Discharge in Cancer Patients with Pericardial Effusion Who Undergo Surgical Pericardial Drainage (ID 2500)

    09:30 - 17:00  |  Author(s): L.L. Lauricella
    • Abstract
    • Slides

    Background:
    Pericardial effusion (PE) is a complication of late-stage cancer and operative pericardial drainage is its standard treatment. However, in many patients PE is an end-of-life event and some never leave the hospital despite the procedure. The main objective of this study was to identify predictors of hospital discharge in patients with cancer who coursed pericardial effusion and underwent operative pericardial drainage. We also looked at predictors of ICU discharge and overall survival and also factors that might be associated with paradoxical hemodynamic instability (PHI).
    
    Methods:
    Retrospective study carried out in a tertiary cancer center. We included all patients with known malignancy who coursed with PE and underwent surgical pericardial drainage from 2011 to 2014. Patients who underwent previous pericardial drainage or only needle pericardiocentesis were excluded from the study.
    
    Results:
    Out of the 90 patients included in this study, fifty one were discharged from hospital (56%). Renal failure and pulmonary embolism negatively influenced the chances of hospital discharge [OR 0,247; p=0,039 and OR 0,293; p=0.089, respectively]. On the other hand, patients who received recent chemotherapy were more likely to leave the hospital (OR 3,9; p=0,009). 55 patients (61%) were discharged from ICU. Renal failure was the main determinant of that (OR 0,284 (p=0,047)). Mean survival was 138.2 days (95% CI 84,48-189,90), influenced only by ECOG status (OR 1,258; p=0,047). PHI occurred in 6 patients and all of them died within 30 days after surgery. In our series, we could not identify predictors for PHI.
    
    Conclusion:
    In this study we demonstrated that almost half of cancer patients admitted with PE requiring drainage never leave the hospital. Renal failure and pulmonary embolism are strong predictors of in-hospital death. PHI remains a serious condition with causes unknown.
    
    

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