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T. Ichikawa



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    P1.19 - Poster Session 1 - Imaging (ID 179)

    • Event: WCLC 2013
    • Type: Poster Session
    • Track: Imaging, Staging & Screening
    • Presentations: 1
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      P1.19-012 - The Quality Of Consolidation In Part Solid Nodule Could Be A Predictor Of Survival (ID 3253)

      09:30 - 16:30  |  Author(s): T. Ichikawa

      • Abstract

      Background
      The size of consolidation on thin-section computed tomography (CT) has been one of the most important preoperative prognostic factors in resected lung cancer. On the other hand, few reports mentioned the nature of consolidation as prognostic factor.

      Methods
      A retrospective study was conducted on 617 lung cancers of clinical stage IA which were resected between 2009 and 2012. Thin-section CT scans were available for all cohorts, which were reviewed by authors. Moreover authors divided lung cancers into three categories: ground glass opacity (GGO), part solid and pure solid. 235 cases are part solid nodule. We classified these 235 part solid lung cancers into two groups: homogeneous or heterogenous. The relationship between these consolidation statuses were evaluated using the chi-square test and Fisher’s exact test. The medical record of each patient was examined for investigating following clinicopathological factors: age, gender, smoking status (pack-year smoking), preoperative serum carcinoembryonic antigen (CEA), SUV max of the primary tumor on positron emission tomography (PET), pathological pleural, vascular, and lymphatic invasion. P-value <0.05 was considered statically significant.

      Results
      Ninety pts (38.3%) had homogeneous consolidation. There were 32 (35.6%) , and 56 (38.6%) men, 6 (14.6%), and tumor having 3 or more SUV max on PET was found in 6 (14.6%), 5 (10.4%), respectively. Based on univariate analysis, age, gender, and pack-year smoking were not statistically significant differences. In homogeneous consolidation group, 2 patients have nodal metastasis, however nodal metastasis were not observed in scattered consolidation group. (P=0.023) Vascular invasive was frequently found in homogeneous consolidation group. (P=0.04)

      Conclusion
      This result of our study shows that the quality of consolidation in part solid lung cancer could be the prognostic factor.

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    P1.20 - Poster Session 1 - Early Detection and Screening (ID 172)

    • Event: WCLC 2013
    • Type: Poster Session
    • Track: Imaging, Staging & Screening
    • Presentations: 1
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      P1.20-011 - Retrospective Study of Lung Cancer Screening. (ID 3372)

      09:30 - 16:30  |  Author(s): T. Ichikawa

      • Abstract

      Background
      The lung cancer screening in Japan is only chest radiography now. But in 2011, the national lung screening trial research team was reported reduced lung-cancer mortality with low-dose computed tomographic screening. We studied lung cancer patients about a difference of a screening type, for example radiography and computed tomography.

      Methods
      From January 2008 through May 2013, we performed the operation of 1344 lung cancer patients. In those patients, 1018 patients were proved the type of screening.

      Results

      symptom radiography CT
      pt 146 340 378
      age 64±1 64±0.7 67±0.5
      cStage IA 50 199 296
      IB 22 66 42
      IIA 18 25 6
      IIB 15 13 8
      IIIA 25 21 12
      IIIB 6 4 2
      IV 7 3 1
      pStage IA 35 155 259
      IB 18 57 53
      IIA 12 31 13
      IIB 16 23 11
      IIIA 41 50 30
      IIIB 6 4 1
      IV 12 7 4
      The number of patients by symptom, radiography and computed tomography are 146 (14%), 340 (33%) and 378 (37%), respectively. The rate of clinical stage I (789, 78%) are 72 (7%), 265 (26%), 338 (33%), respectively. The rate of pathological stage I (672, 66%) are 53 (5%), 212 (21%), 312 (31%), respectively. On the other hand, the rate of clinical III are 31 (3%), 25(2%), 14 (1%), respectively. The rate of pathological III are 47 (5%), 54 (5%), 31 (3%), respectively. The difference of between clinical stage I and screening type are 0.000, 0.813, and 0.000, respectively. The difference of between pathological stage I and screening are 0.000, 0.081, and 0.000, respectively.

      Conclusion
      In the group of symptom and radiography, there are a lot of advanced lung cancer patients, while in the group of computed tomography, we can detect a lot of early lung cancer patients. Computed tomography is better than the other screening about the detecting lung cancer. We should use a computed tomography in screening of lung cancer.